tert-Butyl 7’-fluoro-2’,4’-dihydro-1’H-spiro[piperidine-4,3’-quinoline]-1-carboxylate CAS 1402232-83-0
| CAS No. | 1402232-83-0 |
| Molecular Formula | C18H25FN2O2 |
| Molecular Weight | 320.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
tert-Butyl 7’-fluoro-2’,4’-dihydro-1’H-spiro[piperidine-4,3’-quinoline]-1-carboxylate (CAS 1402232-83-0), molecular formula C18H25FN2O2 and molecular weight 320.40 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of tert-Butyl 7’-fluoro-2’,4’-dihydro-1’H-spiro[piperidine-4,3’-quinoline]-1-carboxylate (C18H25FN2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H25FN2O2 |
| Molecular Weight | 320.40 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- Cocaethylene-D3 (Benzoylecgonine ethyl ester-D3) (CAS 136765-30-5)
- Tert-butyl 5'-fluoro-1',4'-dihydro-2'H-spiro[piperidine-4,3'-quinoline]-1-carboxylate (CAS 1402232-95-4)
- 9-(4-Methoxyphenyl)-9H-xanthene-9-thiol (CAS 132628-15-0)
- Tert-butyl 6'-fluoro-1',4'-dihydro-2'H-spiro[piperidine-4,3'-quinoline]-1-carboxylate (CAS 1439897-52-5)
- 4-({[(4-chlorophenyl)methyl]sulfanyl}methyl)-6-[(4-methylphenyl)sulfanyl]-2-phenylpyrimidine (CAS 338960-72-8)
- Ethyl 3-((tert-butoxycarbonyl)amino)-5-methoxybenzoate (CAS 1292317-96-4)
- Tert-butyl 3-methyl-2,8-diazaspiro[4.5]Decane-2-carboxylate (CAS 1781884-10-3)
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- 2-(3-Cyclopropylisoxazol-5-yl)ethan-1-amine hydrochloride (CAS 2694734-08-0)
- 4-Methylbenzyl (3S,4R)-4-(aminomethyl)-3-fluoropiperidine-1-carboxylate (CAS 808733-20-2)
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- Peptide 433 (CAS CATO-CPTD788433)
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