2-Chloro-4-(2,4-difluorophenyl)-5-fluoropyrimidine CAS 1402545-53-2
| CAS No. | 1402545-53-2 |
| Molecular Formula | C10H4ClF3N2 |
| Molecular Weight | 244.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 2-Chloro-4-(2,4-difluorophenyl)-5-fluoropyrimidine (C10H4ClF3N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 244.60 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
2-Chloro-4-(2,4-difluorophenyl)-5-fluoropyrimidine (CAS 1402545-53-2), molecular formula C10H4ClF3N2 and molecular weight 244.60 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Chloro-4-(2,4-difluorophenyl)-5-fluoropyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H4ClF3N2 |
| Molecular Weight | 244.60 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
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- 1-Chloro-4-(1,1-difluoroethyl)-2-(trifluoromethyl)benzene (CAS 1138444-94-6)
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Recommended Standards
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- 3,5-Dinitro-4-methylbenzoyl chloride (CAS 6633-28-9)
- N-Pentadecane-D32 (CAS 36340-20-2)
- 4-Hydroxy-4,5,6,7-tetrahydro-1-benzofuran-3-carboxylic acid (CAS 1520859-18-0)
- Z-Thr-OH (CAS 19728-63-3)
- N-benzyl-N-(piperidin-3-ylmethyl)propan-2-amine (CAS 1021145-24-3)
- 8-(2-Methoxyphenyl)-8-oxooctanenitrile (CAS 898786-56-6)
- 2,4-Dichloro-1-(4-chlorophenyl)-5-(2,4,6-trifluorophenyl)-1H-imidazole (CAS 1146763-78-1)
- 2-(4-Methyl-2-phenyl-1H-imidazol-5-yl)acetonitrile hydrochloride (CAS 103091-50-5)
- 5-Chloro-1-isopropyl-1H-1,2,4-triazol-3(2H)-one (CAS 42509-62-6)
- 3-(3-Benzyloxyphenyl)-5-nitrobenzoic acid (CAS 1261912-55-3)
- 7-phenyl-1,2,3,4-tetrahydroisoquinoline hydrochloride (CAS 24464-13-9)
- Acetyl Tetrapeptide-11 (CAS 928006-88-6)
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