3-Fluoro-5-nitrobenzoic Acid CAS 14027-75-9
| CAS No. | 14027-75-9 |
| Molecular Formula | C7H4FNO4 |
| Molecular Weight | 185.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-Fluoro-5-nitrobenzoic Acid (C7H4FNO4) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
3-Fluoro-5-nitrobenzoic Acid (CAS 14027-75-9) is a high-purity analytical reference standard with the molecular formula C7H4FNO4 and a molecular weight of 185.11 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Fluoro-5-nitrobenzoic Acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H4FNO4 |
| Molecular Weight | 185.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- 3-Fluoro-2-nitrobenzoic Acid (CAS 1000339-51-4)
- 5-Fluoro-6-nitrobenzo[d][1,3]dioxole (CAS 1366234-02-7)
- 6-Fluoro-3-nitropicolinamide (CAS 171178-31-7)
- 2-Fluoro-3-nitrobenzoic Acid (CAS 317-46-4)
- 2-Fluoro-4-hydroxy-5-nitrobenzaldehyde (CAS 394-34-3)
- 2-Fluoro-6-nitrobenzoic Acid (CAS 385-02-4)
- 3-Fluoro-2-hydroxy-5-nitrobenzaldehyde (CAS 2923-99-1)
- 3-Fluoro-4-hydroxy-5-nitrobenzaldehyde, 97% (CAS 711022-47-8)
Recommended Standards
- 5-fluoropyridine-2,4-dicarboxylic acid (CAS 1427082-33-4)
- 3-Fluoropyridine-2,5-dicarboxylic acid (CAS 1260664-00-3)
- 5-Fluoropyridine-2,3-dicarboxylic acid (CAS 1479-96-5)
- Methyl 2-amino-4,4,4-trifluoro-3-oxobutanoate (CAS 61141-67-1)
- 6-Iodo-3,4-dihydroquinolin-2(1H)-one (CAS 296759-29-0)
- tert-Butyl (2-methylpyridin-3-yl)carbamate (CAS 1219095-87-0)
- 4-Bromo-5,8-dichloroquinoline (CAS 1070879-38-7)
- (4-Ethylthiazol-2-yl)methanamine dihydrochloride (CAS 1262771-85-6)
- (1R,2S,3R,4S)-3-aminobicyclo[2.2.1]Hept-5-ene-2-carboxylic acid hydrochloride (CAS 1242184-45-7)
- benzyl (2S,3S)-2-amino-3-hydroxybutanoate hydrochloride (CAS 780758-27-2)
- 2,5-Bis(5-methylthiophen-2-yl)benzene-1,4-diamine (CAS 2422197-69-9)
- 4-Hydrazinyl-8-(trifluoromethyl)quinoline (CAS 57369-92-3)
- Topiroxostat Impurity 19 (CAS 38634-05-8)
- Semaglutide Impurity 131 (CAS 2618647-80-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com