Benzbromarone EP Impurity B CAS 1402819-05-9
| CAS No. | 1402819-05-9 |
| Molecular Formula | C17H11Br3O3 |
| Molecular Weight | 502.98 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Benzbromarone EP Impurity B meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Benzbromarone EP Impurity B (CAS 1402819-05-9), a pharmacopoeial impurity reference standard (molecular formula C17H11Br3O3, MW 502.98 g/mol) used for the identification and quantification of trace impurities in APIs.
Benzbromarone EP Impurity B (C17H11Br3O3) contains a steroid core, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C17H11Br3O3 |
| Molecular Weight | 502.98 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Br-containing |
Related Benzbromarone Standards
- Benzbromarone Impurity 7 (CAS 152831-00-0 (unlabelled))
- Benzbromarone Impurity 4 (CAS 152831-00-0)
- Benzbromarone-d5 (CAS CATO-C4X-22503)
- Benzbromarone-d4 (CAS CATO-C4X-22502)
- Benzbromarone Impurity 22 (CAS CATO-C4X-225022)
- Benzbromarone (CAS 3562-84-3)
- Benzbromarone Impurity 26 (CAS CATO-C4X-225026)
- Benzbromarone Impurity 27 (CAS CATO-C4X-225027)
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- 1-(Fluoromethyl)cyclopropanamine (CAS 1446084-65-6)
- 6,7-Dihydroindolizin-8(5H)-one (CAS 54906-44-4)
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Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com