3-(Trifluoromethyl)-3-oxetanol CAS 1403676-72-1
| CAS No. | 1403676-72-1 |
| Molecular Formula | C4H5F3O2 |
| Molecular Weight | 142.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-(Trifluoromethyl)-3-oxetanol (C4H5F3O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
3-(Trifluoromethyl)-3-oxetanol (CAS 1403676-72-1), molecular formula C4H5F3O2 and molecular weight 142.08 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-(Trifluoromethyl)-3-oxetanol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C4H5F3O2 |
| Molecular Weight | 142.08 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
Related Trifluoromethyl Standards
- 2-(Trifluoromethyl)-1,3-dioxolane (CAS 2344-09-4)
- 2-Trifluoromethyl-propane-1,3-diamine (CAS 1695963-33-7)
- 3-(trifluoromethyl)-4H-1,2,4-triazole (CAS 60406-75-9)
- 3-(Trifluoromethyl)oxetan-3-amine (CAS 1268954-18-2)
- 2-(trifluoromethyl)-1,3-oxazolidine (CAS 31185-54-3)
- 3-(Trifluoromethyl)azetidin-3-ol (CAS 848392-24-5)
- 3-(Trifluoromethyl)azetidin-3-amine (CAS 1269151-54-3)
- 1-(Trifluoromethyl)cyclobutan-1-ol (CAS 1098183-73-3)
Recommended Standards
- 3,3,3-Trifluoropropyl formate (CAS 1344118-09-7)
- 1,1,1-trifluoro-3-methoxy-propan-2-one (CAS 1512951-75-5)
- 3,3,3-Trifluoro-N-hydroxypropanimidamide (CAS 1016726-53-6)
- 3,3,3-Trifluoro-2-hydroxy-2-methylpropanal (CAS 1525606-70-5)
- 5-Hydroxy-6-methylpyrimidin-4(1H)-one (CAS 65765-96-0)
- Methyl 4-(chloromethyl)-2-methylbenzoate (CAS 1174046-29-7)
- Methyl 2-(((benzyloxy)carbonyl)amino)-2-(4-oxocyclohexyl)acetate (CAS 1543987-22-9)
- 1-(4-Fluoro-2-methoxyphenyl)propan-2-ol (CAS 1532339-94-8)
- 1-(1-Hydroxypropan-2-yl)-4-methylimidazolidin-2-one (CAS 670227-87-9)
- 1-[(5-tert-butyl-1,2,4-oxadiazol-3-yl)methyl]piperazine dihydrochloride (CAS 1315365-26-4)
- 2-Chloro-N-(3-(pyrazin-2-yloxy)phenyl)acetamide (CAS 866157-08-6)
- 2-{[4-(4-chlorophenyl)-5-(pyridin-3-yl)-4h-1,2,4-triazol-3-yl]sulfanyl}acetic acid (CAS 893725-87-6)
- 2-(4-(Difluoromethyl)-5-fluoro-2-(trifluoromethyl)pyridin-3-yl)acetonitrile (CAS 1806882-55-2)
- Semaglutide impurity 54 (CAS CATO-C4X-222654)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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