Mometasone Furoate Impurity 19 CAS 1404070-67-2
| CAS No. | 1404070-67-2 |
| Molecular Formula | C26H28Cl2O6 |
| Molecular Weight | 507.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Mometasone Furoate Impurity 19 (CAS 1404070-67-2, C26H28Cl2O6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Mometasone Furoate Impurity 19 (C26H28Cl2O6) contains a steroid core, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 507.40 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H28Cl2O6 |
| Molecular Weight | 507.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
Related Mometasone Standards
- Mometasone Impurity 30 (CAS CATO-C4X-170430)
- Mometasone Impurity 48 (CAS CATO-C4X-170448)
- Mometasone Furoate EP Impurity P (CAS CATO-C4X-170416)
- Mometasone Furoate EP Impurity H (CAS 148596-90-1)
- Mometasone Impurity 36 (CAS CATO-C4X-170436)
- Mometasone Furoate Impurity 11 (CAS CATO-C4X-170411)
- Mometasone Furoate EP Impurity S (CAS 2231764-75-1)
- Mometasone Furoate Impurity 26 (CAS CATO-C4X-170426)
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