1,3-Difluoro-4-methyl-2-(trifluoromethoxy)benzene CAS 1404194-46-2
| CAS No. | 1404194-46-2 |
| Molecular Formula | C8H5F5O |
| Molecular Weight | 212.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1,3-Difluoro-4-methyl-2-(trifluoromethoxy)benzene (CAS 1404194-46-2), molecular formula C8H5F5O and molecular weight 212.12 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C8H5F5O, 1,3-Difluoro-4-methyl-2-(trifluoromethoxy)benzene contains a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 212.12 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1,3-Difluoro-4-methyl-2-(trifluoromethoxy)benzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5F5O |
| Molecular Weight | 212.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
Related Difluoro Standards
- 2,3-Difluoro-alpha-(trifluoromethyl)benzyl Alcohol (CAS 1343223-64-2)
- 2,3-Difluoro-1-methyl-4-(trifluoromethoxy)benzene (CAS 1404194-74-6)
- (3,5-Difluoro-4-(trifluoromethyl)phenyl)methanol (CAS 1417567-87-3)
- 3,5-Difluoro-4-trifluoromethylanisole (CAS 1429056-37-0)
- (2,4-Difluoro-3-(trifluoromethyl)phenyl)methanol (CAS 1445995-77-6)
- 1,3-Difluoro-4-methoxy-2-(trifluoromethyl)benzene (CAS 1799420-90-8)
- (2,6-Difluoro-3-(trifluoromethyl)phenyl)methanol (CAS 1800231-22-4)
- (2,6-Difluoro-4-(trifluoromethyl)phenyl)methanol (CAS 1803570-73-1)
Recommended Standards
- 6-chloro-5-(chloromethyl)-N,N-dimethylpyrimidin-4-amine (CAS 1375474-11-5)
- 1-(3,5-Difluoropyridin-2-yl)-2,2,2-trifluoroethanamine (CAS 1270394-79-0)
- 5-(Perfluoroethyl)pyridin-2-amine (CAS 1427789-94-3)
- 1-(Difluoromethoxy)-2-(difluoromethyl)-4-fluorobenzene (CAS 1261793-45-6)
- 2-(2-Bromo-5-iodophenyl)acetonitrile (CAS 1261517-16-1)
- 5-Chloro-N-isobutylimidazo[1,2-a]pyrimidin-7-amine (CAS 89099-83-2)
- 2-(2-Bromoethyl)piperidine hydrobromide (CAS 1564-77-8)
- 2-(5-Bromo-6-chloropyridin-3-yl)ethan-1-ol (CAS 2007919-90-4)
- 2-Hydrazino-5-methylpyridine (CAS 4931-01-5)
- 4-(2-Chloro-1,1,2-trifluoroethoxy)-2-methylphenol (CAS 129670-05-9)
- 5-Chloro-2-cyclopropyl-6-(methyl(pyridin-3-ylmethyl)amino)pyrimidine-4-carboxylic acid (CAS 1165936-28-6)
- 8-Hydroxy-7-methyl-3,4-dihydrobenzo[b]oxepin-5(2H)-one (CAS 2226905-18-4)
- Benzylpenicillin Impurity 73 (CAS CATO-C4X-189973)
- (Cys2)-Neuropeptide Y-8-aminooctanoyl-(D-Cys27)-Neuropeptide Y (25-32) (H-3298.0500) (CAS 128806-04-2)
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