4-chloro-1,2-dihydrophthalazine-1-thione CAS 14062-52-3
| CAS No. | 14062-52-3 |
| Molecular Formula | C8H5ClN2S |
| Molecular Weight | 196.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-chloro-1,2-dihydrophthalazine-1-thione (CAS 14062-52-3), molecular formula C8H5ClN2S and molecular weight 196.66 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-chloro-1,2-dihydrophthalazine-1-thione (C8H5ClN2S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-chloro-1,2-dihydrophthalazine-1-thione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5ClN2S |
| Molecular Weight | 196.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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- Coronatine (CAS 62251-96-1)
- Zinc(II) 8-methylnonanoate (CAS 13040-16-9)
- 3-(1h-1,2,3-Triazol-1-yl)benzoic acid (CAS 335255-82-8)
- 2,6-Dibromo-4-iodoaniline (CAS 10527-69-2)
- 1-His-N-a-ethylidene Semaglutide (CAS CATO-C4X-2226252)
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