2-Fluoro-6-hydroxybenzonitrile CAS 140675-43-0
| CAS No. | 140675-43-0 |
| Molecular Formula | C7H4FNO |
| Molecular Weight | 137.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-Fluoro-6-hydroxybenzonitrile (CAS 140675-43-0), molecular formula C7H4FNO and molecular weight 137.11 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Fluoro-6-hydroxybenzonitrile (C7H4FNO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures 2-Fluoro-6-hydroxybenzonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H4FNO |
| Molecular Weight | 137.11 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- 2-Fluoro-3-hydroxybenzonitrile (CAS 1000339-24-1)
- 8-Fluoro-[1,2,4]triazolo[4,3-a]pyridine (CAS 1019026-04-0)
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Recommended Standards
- 4-Hydroxybenzoate 4-Hydroxybenzoate ion 456-23-5 Benzoic acid, 4-hydroxy-, ion(1-) Benzoic acid, p-hydroxy-, ion(1-) p-Hydroxybenzoate p-Hydroxybenzoate anion p-Hydroxybenzoic acid ion(1-) p-Hydroxybenzoic acid monoanion (CAS 456-23-5)
- DL-Malic Acid-2,3,3-d3 (CAS 104596-63-6)
- γ-Fluoro-L-threonine (CAS 89426-34-6)
- SKF-97541 (CAS 127729-35-5)
- tert-Butyl 4-(trifluoromethyl)isoindoline-2-carboxylate (CAS 1194374-84-9)
- 3-(4-Isopropylphenoxy)propan-1-amine (CAS 899425-16-2)
- (4-Bromophenyl)(4-nitrophenyl)sulfane (CAS 21969-12-0)
- 4-Cyclopropylanisole (CAS 4030-17-5)
- Milrinone Impurity 20 (CAS 103977-47-5)
- 1-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperazine hydrochloride (CAS 2088169-24-6)
- Metformin Impurity 107 (CAS CATO-C4X-1065107)
- Rhodamine 6G Bis(aminoethyl)amine Amide Bis (Trifluoroacetate) (CAS 1173097-37-4)
- Pimavanserin Impurity 18 (CAS CATO-C4X-193818)
- Palmitoyl Hexapeptide-12 TFA salt (CAS 171263-26-6(Free Base))
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