Ethyl 4-chloro-5-(trifluoromethyl)picolinate CAS 1407516-45-3
| CAS No. | 1407516-45-3 |
| Molecular Formula | C9H7ClF3NO2 |
| Molecular Weight | 253.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Ethyl 4-chloro-5-(trifluoromethyl)picolinate (CAS 1407516-45-3), molecular formula C9H7ClF3NO2 and molecular weight 253.61 g/mol, is a CATO reference standard with documented purity and traceability.
Ethyl 4-chloro-5-(trifluoromethyl)picolinate (C9H7ClF3NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Ethyl 4-chloro-5-(trifluoromethyl)picolinate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H7ClF3NO2 |
| Molecular Weight | 253.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- Ethyl 2-chloro-5-(trifluoromethyl)nicotinate (CAS 1188265-81-7)
- Ethyl 4-chloro-6-(trifluoromethyl)picolinate (CAS 1196145-47-7)
- Ethyl 2-chloro-6-(trifluoromethyl)isonicotinate (CAS 1196154-43-4)
- Ethyl 3-chloro-4-(trifluoromethyl)picolinate (CAS 1198475-44-3)
- Ethyl 5-chloro-3-(trifluoromethyl)picolinate (CAS 1198475-50-1)
- Ethyl 5-chloro-2-(trifluoromethyl)nicotinate (CAS 1211587-70-0)
- Ethyl 3-chloro-6-(trifluoromethyl)picolinate (CAS 1214332-53-2)
- Ethyl 2-chloro-6-(trifluoromethyl)nicotinate (CAS 1214346-14-1)
Recommended Standards
- Methyl 2-(chloromethyl)-6-(trifluoromethyl)isonicotinate (CAS 1393560-74-1)
- Methyl 4-amino-3-chloro-5-(trifluoromethyl)benzoate (CAS 1476760-57-2)
- Methyl 6-(chloromethyl)-4-(trifluoromethyl)picolinate (CAS 1393543-87-7)
- 4-Chloro-2-Trifluoroacetylaniline (CAS 154598-53-5)
- 5,5-Dimethyl-4-((4S)-4-methyltetrahydro-2H-pyran-2-yl)-4,5-dihydroisoxazole-3-carboxylic acid (CAS 1910205-48-9)
- 3-(Trifluoromethyl)isonicotinaldehyde (CAS 1060801-92-4)
- 2,4-diethyl 3-ethyl-1H-pyrrole-2,4-dicarboxylate (CAS 52921-22-9)
- 0165AD 1185168-21-1 C18H30Cl2N2O N-{[1-(2,3-Dihydro-1H-inden-2-yl)piperidin-4-yl]-methyl}-2-methoxyethanamine dihydrochloride (CAS 1185168-21-1)
- 4-nitro-1H,2H,3H-pyrrolo[2,3-b]pyridin-2-one (CAS 1638763-65-1)
- 3-Chloro-N-phenylbenzamide (CAS 6832-92-4)
- RVX 208 (CAS 1044870-39-4)
- 5-Chloro-1-(2-methoxyethyl)-1H-benzo[d]imidazol-2-amine (CAS 1156754-03-8)
- Ferulic Acid Impurity 4 (CAS 59831-94-6)
- Semaglutide impurity 276 (CAS CATO-C4X-2226276)
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