tert-Butyl (R)-4,4-difluoro-2-(hydroxymethyl)pyrrolidine-1-carboxylate CAS 1407991-22-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1407991-22-3
Molecular FormulaC10H17F2NO3
Molecular Weight237.24 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

tert-Butyl (R)-4,4-difluoro-2-(hydroxymethyl)pyrrolidine-1-carboxylate CAS 1407991-22-3 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including tert-Butyl (R)-4,4-difluoro-2-(hydroxymethyl)pyrrolidine-1-carboxylate.

CATO supplies tert-Butyl (R)-4,4-difluoro-2-(hydroxymethyl)pyrrolidine-1-carboxylate (CAS 1407991-22-3), a certified reference material (molecular formula C10H17F2NO3, MW 237.24 g/mol) for analytical method development and quality control.

tert-Butyl (R)-4,4-difluoro-2-(hydroxymethyl)pyrrolidine-1-carboxylate (C10H17F2NO3) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures tert-Butyl (R)-4,4-difluoro-2-(hydroxymethyl)pyrrolidine-1-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC10H17F2NO3
Molecular Weight237.24 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityLight-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)2.0
CAS Registry Year (est.)1991
Halogen ContentF-containing
Nitrogen Atoms1

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