methyl (2R)-4,4-difluoropyrrolidine-2-carboxylate hydrochloride CAS 1408057-39-5
| CAS No. | 1408057-39-5 |
| Molecular Formula | C6H9F2NO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of methyl (2R)-4,4-difluoropyrrolidine-2-carboxylate hydrochloride (C6H9F2NO2HCl) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
methyl (2R)-4,4-difluoropyrrolidine-2-carboxylate hydrochloride (CAS 1408057-39-5) is a high-purity analytical reference standard with the molecular formula C6H9F2NO2HCl and a molecular weight of 201.60 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H9F2NO2 HCl |
| Molecular Weight | 201.60 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
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- 2-((1-(4-(Methylthio)phenyl)ethyl)amino)ethan-1-ol (CAS 1038368-35-2)
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- tert-Butyl 5-hydroxy-4-oxospiro[chromane-2,4'-piperidine]-1'-carboxylate (CAS 911227-79-7)
- 2-Amino-N-(2-chlorobenzyl)benzamide (CAS 117507-62-7)
- Liraglutide(13-31)TFA Salt (CAS CATO-C4X-19929)
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