trans-3-amino-1-(trifluoromethyl)cyclobutan-1-ol hydrochloride CAS 1408075-16-0
| CAS No. | 1408075-16-0 |
| Molecular Formula | C5H8F3NO |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies trans-3-amino-1-(trifluoromethyl)cyclobutan-1-ol hydrochloride (CAS 1408075-16-0), a certified reference material (molecular formula C5H8F3NOHCl, MW 191.58 g/mol) for analytical method development and quality control.
The molecular framework of trans-3-amino-1-(trifluoromethyl)cyclobutan-1-ol hydrochloride (C5H8F3NOHCl) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), trans-3-amino-1-(trifluoromethyl)cyclobutan-1-ol hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H8F3NO HCl |
| Molecular Weight | 191.58 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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