endo-8-Boc-2-hydroxy-8-azabicyclo[3.2.1]octane CAS 1408075-82-0
| CAS No. | 1408075-82-0 |
| Molecular Formula | C12H21NO3 |
| Molecular Weight | 227.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, endo-8-Boc-2-hydroxy-8-azabicyclo[3.2.1]octane is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 227.30 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
endo-8-Boc-2-hydroxy-8-azabicyclo[3.2.1]octane (CAS 1408075-82-0) is a high-purity analytical reference standard with the molecular formula C12H21NO3 and a molecular weight of 227.30 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), endo-8-Boc-2-hydroxy-8-azabicyclo[3.2.1]octane meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H21NO3 |
| Molecular Weight | 227.30 g/mol |
| Appearance | White to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 1 |
Related endo Standards
- endo-N-Boc-3-hydroxy-8-azabicyclo[3.2.1]octane (CAS 143557-91-9)
- endo-8-Boc-6-hydroxy-8-azabicyclo[3.2.1]octane (CAS 2102411-57-2)
- endo-3-(Boc-amino)-8-azabicyclo[3.2.1]octane (CAS 132234-69-6)
- endo-2-(Boc-amino)-8-azabicyclo[3.2.1]octane (CAS 1408076-01-6)
- endo-8-Boc-8-azabicyclo[3.2.1]octan-2-amine (CAS 1408076-02-7)
- endo-3-Amino-8-azabicyclo[3.2.1]octane-8-carboxylic Acid tert-Butyl Ester (CAS 207405-68-3)
- 3-(3-endo)-8-Azabicyclo[3.2.1]oct-3-ylbenzamide (CAS 949902-11-8)
- Endo-(1s)-1,7,7-Trimethylbicyclo[2.2.1]hept-2-yl chloroacetate (CAS 75556-46-6)
Recommended Standards
- exo-8-Boc-2-hydroxy-8-azabicyclo[3.2.1]octane (CAS 1408074-57-6)
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