3-(3-Chlorophenyl)-5-ethylisoxazole-4-carboxylic acid CAS 1408652-34-5
| CAS No. | 1408652-34-5 |
| Molecular Formula | C12H10ClNO3 |
| Molecular Weight | 251.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(3-Chlorophenyl)-5-ethylisoxazole-4-carboxylic acid.
CATO supplies 3-(3-Chlorophenyl)-5-ethylisoxazole-4-carboxylic acid (CAS 1408652-34-5), a certified reference material (molecular formula C12H10ClNO3, MW 251.67 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 3-(3-Chlorophenyl)-5-ethylisoxazole-4-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 251.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-(3-Chlorophenyl)-5-ethylisoxazole-4-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H10ClNO3 |
| Molecular Weight | 251.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorophenyl Standards
- 2-(2-(2-Chlorophenyl)-5-methyloxazol-4-yl)acetic acid (CAS 1017181-48-4)
- 2-(2-(3-Chlorophenyl)-5-methyloxazol-4-yl)acetic acid (CAS 1017231-31-0)
- 1-(3-Chlorophenyl)-5-ethyl-1h-1,2,3-triazole-4-carboxylic acid (CAS 1017457-41-8)
- 2-[1-(3-chlorophenyl)-5-methyl-1h-1,2,3-triazol-4-yl]acetic acid (CAS 1017457-61-2)
- 1-(2-Chlorophenyl)-5-ethyl-1H-1,2,3-triazole-4-carboxylic acid (CAS 1017458-30-8)
- 6-((2-Chlorophenyl)amino)-3-methylpyrimidine-2,4(1H,3H)-dione (CAS 112069-51-9)
- Ethyl 5-(2-Chlorophenyl)isoxazole-3-carboxylate (CAS 1126636-57-4)
- Methyl 1-(4-Chlorophenyl)-5-methyl-1,2,3-triazole-4-carboxylate (CAS 1147199-25-4)
Recommended Standards
- Methyl 1-[(2-chlorophenyl)methyl]-1H-1,2,4-triazole-3-carboxylate (CAS 1403670-77-8)
- Ethyl 3-(2-chlorophenyl)-1H-1,2,4-triazole-5-carboxylate (CAS 1416339-38-2)
- Methyl 1-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclopropanecarboxylate (CAS 1402446-71-2)
- Methyl 2-(3-(3-chlorophenyl)-1H-1,2,4-triazol-1-yl)acetate (CAS 1416340-62-9)
- (2S)-4-Oxo-2-oxetanecarboxylic Acid Ethyl Ester (CAS 353302-29-1)
- 6-Carboxyl-4-phenyl-3,4-dihydrocoumarin (CAS 356782-33-7)
- N-[5-chloro-2-(1H-1,2,4-triazol-1-yl)phenyl]-2-{[1-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methylpropyl]amino}acetamide (CAS 940859-53-0)
- 1-[5-(butan-2-yl)-1H-1,2,4-triazol-3-yl]ethan-1-amine hydrochloride (CAS 1787904-43-1)
- (+)-2-Amino-2-(4-bromophenyl)acetic acid (CAS 119397-06-7)
- 1,8-Dimethylnaphthalene-d12 (CAS 104489-29-4)
- Formamide-1-d1 (CAS 35692-88-7)
- Benzyl 2-(tert-butyl)-3-methyl-4-oxoimidazolidine-1-carboxylate (CAS 111610-19-6)
- Ampicillin Impurity 81 (CAS CATO-C4X-144381)
- Glucagon Monohydrochloride (CAS 28270-04-4)
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