8-Chloro-3-cyclopropyl-[1,2,4]triazolo[4,3-a]pyrazine CAS 140911-01-9
| CAS No. | 140911-01-9 |
| Molecular Formula | C8H7ClN4 |
| Molecular Weight | 194.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 8-Chloro-3-cyclopropyl-[1,2,4]triazolo[4,3-a]pyrazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 8-Chloro-3-cyclopropyl-[1,2,4]triazolo[4,3-a]pyrazine (CAS 140911-01-9), a certified reference material (molecular formula C8H7ClN4, MW 194.62 g/mol) for analytical method development and quality control.
The molecular framework of 8-Chloro-3-cyclopropyl-[1,2,4]triazolo[4,3-a]pyrazine (C8H7ClN4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H7ClN4 |
| Molecular Weight | 194.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
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Recommended Standards
- 5-[(4-chlorophenyl)methyl]-2h-1,2,3,4-tetrazole (CAS 14064-61-0)
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- 3-Chloro-5-(m-tolyl)-1,2,4-oxadiazole (CAS 1393568-61-0)
- 1-(7-Chloro-1H-pyrrolo[2,3-c]pyridin-3-yl)ethan-1-one (CAS 1427502-49-5)
- 4-(N-Benzyl-N-methylsulfamoyl)benzoic acid (CAS 887202-40-6)
- O-Benzoyl-N-isobutylhydroxylamine (CAS 92787-70-7)
- 2-Bromo-6-iodo-3-methylpyridine (CAS 1805025-35-7)
- 2-Bromo-5-(difluoromethyl)-4-methoxypyridin-3-ol (CAS 1807000-49-2)
- Bifonazole Impurity 12 (CAS CATO-C4X-156012)
- 3-Amino-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxylic acid (CAS 166113-90-2)
- 5-Fluoro-1,2,3,4-tetrahydroisoquinoline hydrochloride (CAS 799274-07-0)
- N-[3-(Trifluoromethyl)benzyl]piperidin-4-amine dihydrochloride (CAS 1707602-13-8)
- 1-(5-Methylpyridin-2-yl)ethanamine dihydrochloride (CAS 1187931-95-8)
- Tirzepatide Impurity 19 X TFA Salt (CAS CATO-C4X-324019)
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