4-(3,4,5-Trifluorophenyl)butanoic acid CAS 1410187-01-7
| CAS No. | 1410187-01-7 |
| Molecular Formula | C10H9F3O2 |
| Molecular Weight | 218.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-(3,4,5-Trifluorophenyl)butanoic acid (CAS 1410187-01-7) is a high-purity analytical reference standard with the molecular formula C10H9F3O2 and a molecular weight of 218.17 g/mol.
The molecular framework of 4-(3,4,5-Trifluorophenyl)butanoic acid (C10H9F3O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H9F3O2 |
| Molecular Weight | 218.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
Related Trifluorophenyl Standards
- Ethyl 2-(2,3,6-trifluorophenyl)acetate (CAS 114152-22-6)
- Ethyl 2-(2,4,5-trifluorophenyl)acetate (CAS 1256470-41-3)
- Ethyl 2-(2,3,4-trifluorophenyl)acetate (CAS 1256479-43-2)
- Ethyl 2-(2,3,5-trifluorophenyl)acetate (CAS 1256479-84-1)
- 2-(2,3,4-Trifluorophenyl)butanoic acid (CAS 1342382-96-0)
- (2,3,5-Trifluorophenyl)acetic acid Ethyl ester (CAS 773135-01-6)
- Ethyl 2-(2,4,6-trifluorophenyl)acetate (CAS 835878-81-4)
- Ethyl 2-(3,4,5-trifluorophenyl)acetate (CAS 238743-47-0)
Recommended Standards
- 2-(4-(2,2,2-Trifluoroethyl)phenyl)acetic acid (CAS 1393561-66-4)
- Ethyl 4-(difluoromethyl)-3-fluorobenzoate (CAS 1417459-60-9)
- 8-Hydroxy-5-nitroquinoline-7-carbaldehyde (CAS 13785-22-3)
- 2-Methyl-6-(trifluoromethyl)-6,7-dihydrobenzofuran-4(5H)-one (CAS 1420791-34-9)
- 4-(5-(Methoxycarbonyl)-1h-pyrrol-3-yl)-4-oxobutanoic acid (CAS 1421602-36-9)
- Netupitant N-Oxide (CAS 910808-11-6)
- 5-Chloro-3-(2-ethoxyethoxy)thiophene-2-carboxylic acid (CAS 1707372-08-4)
- 5-Chloro-2-methylsulfanyl-4-tribuylstannanylpyrimidine (CAS 123061-47-2)
- N-Methoxy-N,3-dimethyl-3H-imidazo[4,5-b]pyridine-6-carboxamide (CAS 1186310-78-0)
- 2-Methyl-6-phenoxynicotinic acid (CAS 1355189-31-9)
- (S)-2-((2-(Trifluoromethyl)phenoxy)methyl)oxirane (CAS 134598-04-2)
- 4-CHloro-2-hydroxy-6-methoxybenzaldehyde (CAS 1427396-66-4)
- 2-(tert-Butyl)-6-chloropyrimidin-4(3H)-one (CAS 1504059-41-9)
- Des-His(1)-Semaglutide (CAS CATO-C4X-2226216)
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