Epinastine EP Impurity A(Hydrochloride) CAS 141342-70-3
| CAS No. | 141342-70-3 |
| Molecular Formula | C16H13N3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Epinastine EP Impurity A(Hydrochloride) (CAS 141342-70-3) is a certified pharmaceutical impurity reference standard with the molecular formula C16H13N3HCl and a molecular weight of 283.76 g/mol.
The molecular framework of Epinastine EP Impurity A(Hydrochloride) (C16H13N3HCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Epinastine EP Impurity A(Hydrochloride) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H13N3 HCl |
| Molecular Weight | 283.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Epinastine Standards
- Epinastine Impurity 24 (CAS 1110929-19-5)
- Epinastine Impurity 53 (CAS 114-39-6)
- Epinastine Related Compound A HCl (CAS 1159604-26-8)
- Epinastine Impurity 6 (CAS 1211-06-9)
- Epinastine Impurity 3 (CAS 1216548-20-7)
- Epinastine EP Impurity B (CAS 1217052-16-8)
- Epinastine Impurity 22 (CAS 124847-00-3)
- Epinastine Impurity 44 Fumarate (CAS 127785-96-0)
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- endo-Ser39-Tirzepatide (CAS CATO-CPTD788935)
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