1-(4-Bromo-3-chlorobenzyl)piperidine CAS 1414870-61-3
| CAS No. | 1414870-61-3 |
| Molecular Formula | C12H15BrClN |
| Molecular Weight | 288.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-(4-Bromo-3-chlorobenzyl)piperidine (C12H15BrClN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
1-(4-Bromo-3-chlorobenzyl)piperidine (CAS 1414870-61-3) is a high-purity analytical reference standard with the molecular formula C12H15BrClN and a molecular weight of 288.61 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(4-Bromo-3-chlorobenzyl)piperidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H15BrClN |
| Molecular Weight | 288.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 1-(4-Bromo-2-chlorophenyl)methylpiperidine (CAS 1200131-41-4)
- N-[(4-BRomo-3-chlorophenyl)methyl]cyclopentanamine (CAS 1539241-83-2)
- 1-[(3-Bromo-4-chlorophenyl)methyl]piperidine (CAS 1881320-84-8)
- 3-Bromo-2-chloro-6-((trimethylsilyl)ethynyl)pyridine (CAS 2508627-84-5)
- 5-Bromo-2-chloro-N-cyclobutylbenzamide (CAS 1249987-62-9)
- 5-(2-Bromo-4-chlorophenoxy)pentanenitrile (CAS 1250482-14-4)
- 1-(2-Bromo-4-chlorophenyl)piperidin-2-one (CAS 1255574-59-4)
- 3-Bromo-7-chloro-6-isopropyl-5-methylpyrazolo[1,5-a]pyrimidine (CAS 1310287-68-3)
Recommended Standards
- 2,2,2-Trichloroacetimidic Acid 4-Methoxybenzyl Ester 4-Methoxybenzyl 2,2,2-Trichloroacetimidate 89238-99-3 M2016 (CAS 89238-99-3)
- 4-(Difluoromethyl)-5-hydroxy-3-nitropyridine-2-sulfonyl chloride (CAS 1805394-10-8)
- 2,7-Dichloro-3-(3-chloropropyl)-8-methylquinoline (CAS 948292-07-7)
- 2-(Difluoromethyl)-5-hydroxy-4-nitropyridine-3-sulfonyl chloride (CAS 1805540-51-5)
- 3-(2-([1,1':4',1''-Terphenyl]-4-yl)vinyl)-9-phenyl-9H-carbazole (CAS 1335148-56-5)
- 1-(1-Cyclopropyl-1H-pyrrol-2-yl)ethanone (CAS 925430-05-3)
- [1,2,4]triazolo[1,5-a]pyrimidin-2-amine (CAS 13223-53-5)
- 8-Oxo-7,8-dihydro-1,7-naphthyridine-3-carbonitrile (CAS 1823968-71-3)
- Mono-6-O-(p-toluenesulfonyl)-γ-cyclodextrin (CAS 97227-33-3)
- (R)-2-Amino-3-(thiazol-2-yl)propanoic acid (CAS 134235-87-3)
- Tert-butyl 7-chlorospiro[indoline-3,4'-piperidine]-1'-carboxylate (CAS 1822826-73-2)
- 2-Amino-N'-phenylbenzohydrazide (CAS 30086-49-8)
- Cyclobutyl 2-(4-methoxyphenyl)ethyl ketone (CAS 898793-78-7)
- CGMP Dependent Kinase Inhibitor Peptide (CAS 82801-73-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com