tert-Butyl ((2R,4R,5S)-5-amino-4-hydroxy-1,6-diphenylhexan-2-yl)carbamate (Ritonavir Impurity ) CAS 1414933-85-9
| CAS No. | 1414933-85-9 |
| Molecular Formula | C23H32N2O3 |
| Molecular Weight | 384.51 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
tert-Butyl ((2R,4R,5S)-5-amino-4-hydroxy-1,6-diphenylhexan-2-yl)carbamate (Ritonavir Impurity ) (CAS 1414933-85-9) is a certified pharmaceutical impurity reference standard with the molecular formula C23H32N2O3 and a molecular weight of 384.51 g/mol.
Structurally, tert-Butyl ((2R,4R,5S)-5-amino-4-hydroxy-1,6-diphenylhexan-2-yl)carbamate (Ritonavir Impurity ) (C23H32N2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 384.51 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), tert-Butyl ((2R,4R,5S)-5-amino-4-hydroxy-1,6-diphenylhexan-2-yl)carbamate (Ritonavir Impurity ) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H32N2O3 |
| Molecular Weight | 384.51 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 2 |
Recommended Standards
- tert-Butyl ((2S,4R,5S)-5-amino-4-hydroxy-1,6-diphenylhexan-2-yl)carbamate (Ritonavir Impurity ) (CAS 1414933-83-7)
- tert-Butyl ((2S,4R,5R)-5-amino-4-hydroxy-1,6-diphenylhexan-2-yl)carbamate (CAS 1414933-89-3)
- Tert-butyl 4-(2'-oxospiro[cyclohexane-1,3'-indolin]-1'-yl)piperidine-1-carboxylate (CAS 1358667-62-5)
- tert-Butyl ((2S,4S,5R)-5-amino-4-hydroxy-1,6-diphenylhexan-2-yl)carbamate (CAS 1414933-91-7)
- Bupivacaine Impurity 41 (CAS 760928-28-7)
- Lubiprostone Impurity 24 (CAS 32233-41-3)
- Loxoprofen Impurity 42 (CAS CATO-C4X-148842)
- 1,2-Dimethyl-1H-benzo[d]imidazole-5-sulfonamide (CAS 1330750-84-9)
- (S)-2-((tert-Butoxycarbonyl)amino)-3-((tert-butyldiphenylsilyl)oxy)propanoic acid (CAS 145790-51-8)
- rel-(2R,4S)-1-(tert-butoxycarbonyl)-4-hydroxypiperidine-2-carboxylic acid (CAS 1217699-64-3)
- 4-Methyl-1H-benzo[d]imidazol-6-ol (CAS 1231749-80-6)
- 2-(1,2,3,4-Tetrahydronaphthalen-1-yl)acetonitrile (CAS 61677-91-6)
- Zopiclone-d8 (CAS 1215518-83-4)
- D-Gln24-Tirzepatide (CAS CATO-CPTD788910)
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