(R)-2-(1-Amino-7-bromo-1,2,3,4-tetrahydronaphthalen-1-yl)-2,2-difluoroethanol CAS 1415108-40-5
| CAS No. | 1415108-40-5 |
| Molecular Formula | C12H14BrF2NO |
| Molecular Weight | 306.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 306.15 g/mol gives (R)-2-(1-Amino-7-bromo-1,2,3,4-tetrahydronaphthalen-1-yl)-2,2-difluoroethanol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(R)-2-(1-Amino-7-bromo-1,2,3,4-tetrahydronaphthalen-1-yl)-2,2-difluoroethanol (CAS 1415108-40-5) is a high-purity analytical reference standard with the molecular formula C12H14BrF2NO and a molecular weight of 306.15 g/mol.
The molecular framework of (R)-2-(1-Amino-7-bromo-1,2,3,4-tetrahydronaphthalen-1-yl)-2,2-difluoroethanol (C12H14BrF2NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (R)-2-(1-Amino-7-bromo-1,2,3,4-tetrahydronaphthalen-1-yl)-2,2-difluoroethanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H14BrF2NO |
| Molecular Weight | 306.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related R Standards
- Benzyl 2-amino-5-bromobenzoate (CAS 1131587-72-8)
- [2-Amino-3-(hydroxymethyl)phenyl]methanone (CAS 1797130-42-7)
- 2-amino-6-iodo-1,8-naphthyridine-3-carbonitrile 2-azanyl-6-iodanyl-1,8-naphthyridine-3-carbonitrile 578007-69-9 A831610 (CAS 578007-69-9)
- Ethyl 5-amino-4-bromo-1-(2-ethoxyethyl)-1H-pyrazole-3-carboxylate (CAS 1427013-70-4)
- 5-Amino-1-(4-bromophenyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS 1416344-67-6)
- 5-Amino-1-(3-bromophenyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS 1416346-25-2)
- 2-amino-8-(4-bromophenyl)-6,9-dihydro-1H-purin-6-one (CAS 79953-09-6)
- 4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2(1H)-selenone (CAS 63676-55-1)
Recommended Standards
- N-(2,6-Dichlorophenyl)-1H-pyrrolo[2,3-b]pyridine-4-carboxamide (CAS 1403667-44-6)
- 1-(2-Bromo-4-(difluoromethyl)phenyl)piperidin-4-ol (CAS 1704073-27-7)
- 6-bromo-2-cyclopropyl-3-methylquinoline-4-carboxylic acid (CAS 1376013-52-3)
- 4-(Benzyloxy)-3-bromobenzamide (CAS 1706456-92-9)
- 6-Fluoro-3-methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile (CAS 2253959-58-7)
- N-[(Tetrahydro-4-phenyl-2H-pyran-4-yl)methyl]acetamide (CAS 14006-33-8)
- 2-(Benzylthio)-5-nitrobenzonitrile (CAS 175135-67-8)
- Firocoxib Impurity 6 (CAS CATO-C4X-32116)
- Cnx-1351 (CAS 1276105-89-5)
- 2-Bromo-3-methoxy-4-(trifluoromethyl)pyridine (CAS 1227593-98-7)
- Bazedoxifene Bis-β-D-Glucuronide (CAS 328933-67-1)
- Methyl 2-chlorooxazolo[4,5-c]pyridine-6-carboxylate (CAS 1260665-37-9)
- (R)-N-(32-Azido-3,6,9,12,15,18,21,24,27,30-decaoxadotriacontyl)-5-(1,2-dithiolan-3-yl)pentanamide (CAS 1459140-82-9)
- (Tyr?)-C-Peptide (dog) (CAS 101135-67-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com