(R)-2-(4-Amino-6-bromochroman-4-yl)-2,2-difluoroethanol CAS 1415108-80-3
| CAS No. | 1415108-80-3 |
| Molecular Formula | C11H12BrF2NO2 |
| Molecular Weight | 308.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies (R)-2-(4-Amino-6-bromochroman-4-yl)-2,2-difluoroethanol (CAS 1415108-80-3), a certified reference material (molecular formula C11H12BrF2NO2, MW 308.12 g/mol) for analytical method development and quality control.
The molecular framework of (R)-2-(4-Amino-6-bromochroman-4-yl)-2,2-difluoroethanol (C11H12BrF2NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H12BrF2NO2 |
| Molecular Weight | 308.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- 3-((3-Chlorophenyl)amino)cyclohex-2-en-1-one (CAS 51409-82-6)
- 3-Hydroxy-5-[4-(trifluoromethyl)phenyl]cyclohex-2-ene-1-one (CAS 110165-98-5)
- 2,5-Dichloro-N-(5-methoxy-2-methylphenyl)pyrimidin-4-amine (CAS 1986882-81-8)
- 2-Bromo-3-hydroxybenzyl chloride (CAS 1260674-44-9)
- 5-Ethyl 6-methyl-2,5-pyridinedicarboxylate (CAS 890302-07-5)
- 6-Bromo-8-methoxy-2-oxo-2H-chromene-3-carboxylic acid (CAS 119686-34-9)
- H-α-Difluoro-Me-DL-Orn-OH · HCl · H2O (CAS 96020-91-6)
- Acetyl tetrapeptide-3 (CAS 827306-88-7)
Why CATO?
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