Pheniramine Impurity 1 CAS 14155-36-3
| CAS No. | 14155-36-3 |
| Molecular Formula | C9H10Cl2 |
| Molecular Weight | 189.08 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Pheniramine Impurity 1 is closely related to chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Pheniramine Impurity 1 (CAS 14155-36-3) is a certified pharmaceutical impurity reference standard with the molecular formula C9H10Cl2 and a molecular weight of 189.08 g/mol.
Pheniramine Impurity 1 (C9H10Cl2) contains chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Pheniramine Impurity 1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H10Cl2 |
| Molecular Weight | 189.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
Related Pheniramine Standards
Recommended Standards
- 57386-83-1 Benzene, 2,4-dichloro-1,3,5-trimethyl- CTK1F2174 (CAS 57386-83-1)
- 2,4-Dichloro-1-isopropylbenzene (CAS 65432-03-3)
- 1-Bromo-4,4-dimethylcyclohex-1-ene (CAS 1020253-13-7)
- 1-Chloro-4-(3-chloropropyl)benzene (CAS 64473-34-3)
- Tildipirosin impurity 4 (CAS CATO-C4X-32764)
- Vericiguat Impurity 75 (CAS CATO-C4X-289675)
- Josamycin EP Impurity H (KitasaMycin A1) (CAS 16846-34-7)
- N-(4-Amino-2-methylphenyl)-2-propoxybenzamide (CAS 1020057-81-1)
- Ethyl (4aR,9bS)-6-bromo-1,2,3,4,4a,9b-hexahydro-5H-pyrido[4,3-b]indole-5-carboxylate (CAS 2306245-42-9)
- 3H-Pyrazolo[4,3-b]pyridin-3-amine (CAS 132643-73-3)
- n-(1h-Indazol-3-yl)cyclopropanecarboxamide (CAS 1088155-94-5)
- 4-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)phenoxy]-2-trifluoromethylbenzonitrile (CAS 1367127-44-3)
- 6-Hydroxy-2-oxo-4-phenyl-1,2-dihydropyridine-3,5-dicarbonitrile (CAS 20964-63-0)
- Des-Tyr10-Tirzepatide (CAS CATO-CPTD788680)
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