Avibactam Impurity 131 CAS 1416134-59-2
| CAS No. | 1416134-59-2 |
| Molecular Formula | C20H29ClN2O5 |
| Molecular Weight | 412.91 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 412.91 g/mol gives Avibactam Impurity 131 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Avibactam Impurity 131 (CAS 1416134-59-2, C20H29ClN2O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Avibactam Impurity 131 (C20H29ClN2O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Avibactam Impurity 131 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H29ClN2O5 |
| Molecular Weight | 412.91 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Avibactam Standards
- Avibactam Impurity 38 (CAS 2381511-26-6)
- Avibactam Impurity 117 (CAS CATO-C4X-1348117)
- Avibactam Impurity 115 (CAS 1510832-19-5)
- Avibactam Impurity 120 (CAS CATO-C4X-1348120)
- Avibactam Impurity 123 (CAS CATO-C4X-1348123)
- Avibactam Impurity 136 (CAS CATO-C4X-1348136)
- Avibactam Impurity 137 (CAS CATO-C4X-1348137)
- Avibactam Impurity 151 (CAS CATO-C4X-1348151)
Recommended Standards
- 4-((4-Chlorophenyl)sulfonyl)-N-(3-methoxypropyl)-2-(thiophen-2-yl)oxazol-5-amine (CAS 627834-73-5)
- 2-Chloro-9,10-bis(phenylethynyl)anthracene (CAS 41105-36-6)
- ethyl 4-(8-chloro-4-(hydroxymethyl)-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate (CAS 609806-40-8)
- 1-Chloro-9,10-bis(phenylethynyl)anthracene (CAS 41105-35-5)
- Pitavastatin Impurity 47 (CAS CATO-C4X-103747)
- Ciclesonide Impurity 1 (CAS 1005416-98-7)
- Faropenem Impurity 25 (CAS CATO-C4X-128925)
- N1-(2-aminophenyl)-N8-phenyloctanediamide (CAS 537034-17-6)
- m-PEG3-NHS ester (CAS 876746-59-7)
- Lanabecestat camsylate, >98% (HPLC) (CAS 1522418-41-2)
- 4,4-Dimethyl-2-(2-(trifluoromethyl)phenyl)-4,5-dihydrooxazole (CAS 263382-53-2)
- 4-(3,5-Dimethoxyphenyl)-5-(phenoxymethyl)-4H-1,2,4-triazole-3-thiol (CAS 917747-01-4)
- rel-(1S,2R)-2-Amino-1,2-diphenylethanol (CAS 23412-95-5)
- Liraglutide Impurity 28 (CAS CATO-C4X-199228)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com