1-(Naphthalen-1-yl)-2-(trifluoromethyl)pyrrolidine CAS 1416374-52-1
| CAS No. | 1416374-52-1 |
| Molecular Formula | C15H14F3N |
| Molecular Weight | 265.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
1-(Naphthalen-1-yl)-2-(trifluoromethyl)pyrrolidine (CAS 1416374-52-1), molecular formula C15H14F3N and molecular weight 265.27 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(Naphthalen-1-yl)-2-(trifluoromethyl)pyrrolidine (C15H14F3N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 1-(Naphthalen-1-yl)-2-(trifluoromethyl)pyrrolidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H14F3N |
| Molecular Weight | 265.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Naphthalen Standards
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- 4-(Naphthalen-1-yl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine (CAS 1255099-05-8)
- 1-(Naphthalen-1-yl)-3-(pyrimidin-2-yl)urea (CAS 24386-39-8)
- 2-Naphthalen-1-yloxybenzoic acid (CAS 613669-18-4)
- N'-(Naphthalen-1-ylmethylene)furan-2-carbohydrazide (CAS 292180-86-0)
- Naphthalen-2-yl 2-hydroxybenzoate (CAS 613-78-5)
- Naphthalen-2-ylmethyl pyrazine-2-carboxylate (CAS 791788-80-2)
Recommended Standards
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- Ethyl 2-(ethylamino)-3-(1h-pyrazol-1-yl)propanoate (CAS 1248226-17-6)
- Peptide YY (3-36) (canine, mouse, porcine, rat) trifluoroacetate salt (CAS 126339-09-1)
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