2-bromo-3-fluoro-pyridin-4-amine CAS 1417638-80-2
| CAS No. | 1417638-80-2 |
| Molecular Formula | C5H10BrFN2 |
| Molecular Weight | 197.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-bromo-3-fluoro-pyridin-4-amine is closely related to fluorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-bromo-3-fluoro-pyridin-4-amine (CAS 1417638-80-2), a certified reference material (molecular formula C5H10BrFN2, MW 197.05 g/mol) for analytical method development and quality control.
The molecular framework of 2-bromo-3-fluoro-pyridin-4-amine (C5H10BrFN2) is characterized by fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-bromo-3-fluoro-pyridin-4-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H10BrFN2 |
| Molecular Weight | 197.05 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
Related bromo Standards
- 5-bromo-2-fluoropyridin-4-amine (CAS 1232430-97-5)
- 3-bromo-6-fluoro-pyridin-2-amine (CAS 1232431-41-2)
- 6-bromo-5-fluoropyridin-2-amine (CAS 1257294-51-1)
- 6-bromo-3-fluoropyridin-2-amine (CAS 1379457-78-9)
- 3-bromo-4-fluoro-pyridin-2-amine (CAS 1417407-29-4)
- 4-bromo-3-fluoro-pyridin-2-amine (CAS 1417532-98-9)
- 2-Bromo-5-fluorophenol (CAS 147460-41-1)
- 2-bromo-5-fluoropyridin-4-amine (CAS 887570-94-7)
Recommended Standards
- 2,2'-Selenodiacetic acid (CAS 6228-62-2)
- 3-Bromo-2,3-dihydro-thiophene 1,1-dioxide (CAS 53336-42-8)
- 4-(bromomethyl)-4-fluorooxane (CAS 1240951-88-5)
- 5-Bromo-2,3-dihydrothiophene 1,1-dioxide (CAS 56879-03-9)
- 1-(4-Fluorophenyl)-1,2-ethanediol (CAS 17951-22-3)
- 2,3-Dimethyl-2-butene (CAS 563-79-1)
- (E)-3-(3-Chloro-4-methylphenyl)acrylic acid (CAS 220353-90-2)
- 1-{[4-(2,2,2-trifluoroethoxy)phenyl]methyl}piperazine dihydrochloride (CAS 1333970-65-2)
- 2-Chloro-N-phenylnicotinamide (CAS 56149-29-2)
- Tirofiban Impurity 66 DiHCl (CAS CATO-C4X-125466)
- tert-butyl (3R,4R)-3-fluoro-4-methylsulfonyloxy-pyrrolidine-1-carboxylate (CAS 1610417-31-6)
- 1-Cyclopropyl-3-methoxy-1H-pyrazole-4-carboxylic acid (CAS 2388475-17-8)
- 6-Ethynylnicotinaldehyde (CAS 1047627-04-2)
- Insulin Degludec Impurity 26 (CAS CATO-C4X-215726)
Why CATO?
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