Thiazolo[5,4-c]pyridine-2-carbonitrile CAS 1417816-72-8
| CAS No. | 1417816-72-8 |
| Molecular Formula | C7H3N3S |
| Molecular Weight | 161.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Thiazolo[5,4-c]pyridine-2-carbonitrile (C7H3N3S) is characterized by a nitrile group, sulfur-containing functionality, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Thiazolo[5,4-c]pyridine-2-carbonitrile (CAS 1417816-72-8) is a high-purity analytical reference standard with the molecular formula C7H3N3S and a molecular weight of 161.18 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H3N3S |
| Molecular Weight | 161.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Thiazolo Standards
- Thiazolo[4,5-c]pyridine-4-carbonitrile (CAS 1332387-68-4)
- thiazolo[5,4-b]pyridin-2-amine (CAS 31784-70-0)
- Thiazolo[4,5-b]pyridine-6-carbaldehyde (CAS 1367917-16-5)
- [1,3]thiazolo[5,4-b]pyridine-2-carbaldehyde (CAS 1480005-25-1)
- Thiazolo[4,5-c]pyridine-2-carbaldehyde (CAS 97249-56-4)
- Thiazolo[4,5-c]pyridin-2-ylmethanamine (CAS 1203605-29-1)
- Thiazolo[5,4-b]pyridin-2-ylmethanamine (CAS 1203605-30-4)
- Thiazolo[5,4-b]pyridin-5-ylmethanamine (CAS 1313726-14-5)
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