8-Fluoro-5-iodoquinoline CAS 1420791-37-2
| CAS No. | 1420791-37-2 |
| Molecular Formula | C9H5FIN |
| Molecular Weight | 273.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
8-Fluoro-5-iodoquinoline (CAS 1420791-37-2) is a high-purity analytical reference standard with the molecular formula C9H5FIN and a molecular weight of 273.05 g/mol.
The molecular framework of 8-Fluoro-5-iodoquinoline (C9H5FIN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 8-Fluoro-5-iodoquinoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H5FIN |
| Molecular Weight | 273.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- 7-Fluoro-1-iodoisoquinoline (CAS 1207448-25-6)
- 5-Fluoro-1-iodoisoquinoline (CAS 1207448-31-4)
- 7-Fluoro-3-iodoquinoline (CAS 1416440-27-1)
- 5-Fluoro-8-iodoquinoline (CAS 1420790-38-0)
- 6-Fluoro-5-iodoquinoline (CAS 1420790-80-2)
- 7-Fluoro-8-iodoquinoline (CAS 1420793-95-8)
- 6-Fluoro-3-iodoquinoline (CAS 1802820-04-7)
- 3-Fluoro-6-iodoquinoline (CAS 1823901-86-5)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com