7-Chloro-1-(prop-2-yn-1-yl)quinolin-2(1H)-one CAS 1420792-18-2
| CAS No. | 1420792-18-2 |
| Molecular Formula | C12H8ClNO |
| Molecular Weight | 217.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 7-Chloro-1-(prop-2-yn-1-yl)quinolin-2(1H)-one is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 7-Chloro-1-(prop-2-yn-1-yl)quinolin-2(1H)-one (CAS 1420792-18-2), a certified reference material (molecular formula C12H8ClNO, MW 217.65 g/mol) for analytical method development and quality control.
The molecular framework of 7-Chloro-1-(prop-2-yn-1-yl)quinolin-2(1H)-one (C12H8ClNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 7-Chloro-1-(prop-2-yn-1-yl)quinolin-2(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H8ClNO |
| Molecular Weight | 217.65 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 8-Chloro-7-fluoro-2H-benzo[b][1,4]thiazin-3(4H)-one (CAS 101337-95-5)
- 6-Chloro-N-(2,2-dimethoxyethyl)pyrimidin-4(3H)-imine (CAS 1159822-73-7)
- 1-Chloro-10H-phenoxazine (CAS 116366-11-1)
- 6-Chloro-4-fluoro-2-hydrazinylbenzo[d]thiazole (CAS 1177300-26-3)
- (2-Chloro-3-(dimethoxymethyl)pyridin-4-yl)methanol (CAS 1186310-66-6)
- 5-Chloro-2-phenylisonicotinaldehyde (CAS 1227582-75-3)
- Methyl 3-(4-chloro-1h-pyrazol-1-yl)-2-(methylamino)propanoate (CAS 1250847-38-1)
- 3-(4-Chloro-1h-pyrazol-1-yl)-2-methyl-2-(methylamino)propanoic acid (CAS 1251244-35-5)
Recommended Standards
- 3-Chloro-N-(2,2-dimethoxyethyl)pyrazin-2-amine (CAS 1417361-15-9)
- 5-Chloro-1-(prop-2-yn-1-yl)quinolin-2(1H)-one (CAS 1420793-56-1)
- 6-Chloro-9H-pyrido[3,4-b]indol-3-amine (CAS 1376918-23-8)
- 6-Chloro-1-(prop-2-yn-1-yl)quinolin-2(1H)-one (CAS 1420794-92-8)
- N-Ethyl-4-hydroxy-N-methylpyridine-3-sulfonamide (CAS 1340273-08-6)
- 2,5-Dimethylquinolin-8-ol (CAS 10522-43-7)
- 1,3-Bis(1-methyl-1H-benzo[d]imidazol-2-yl)benzene (CAS 141045-26-3)
- 1-(4-Bromophenyl)-3-((4-(sec-butyl)phenyl)amino)propan-1-one (CAS 882748-25-6)
- Ethyl (3-hydroxypropyl) carbonate (CAS 62502-19-6)
- Saterinone (CAS 102669-89-6)
- (4S)-4-Amino-5,5,5-trifluoro-4-(4-methylphenyl)pentan-2-one (CAS 1030852-38-0)
- 4-(4-(Dimethylamino)piperidin-1-yl)-2-nitrobenzaldehyde 1707357-95-6 (CAS 1707357-95-6)
- Tert-butyl cyclopropyl(3-(thietan-3-ylamino)propyl)carbamate (CAS 1994192-69-6)
- Amyloid Precursor Frameshift Mutant C-Terminal Peptide trifluoroacetate salt (CAS 189125-14-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com