Osimertinib CAS 1421373-65-0
| CAS No. | 1421373-65-0 |
| Molecular Formula | C28H33N7O2 |
| Molecular Weight | 499.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Osimertinib is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Osimertinib (CAS 1421373-65-0) is a high-purity analytical reference standard with the molecular formula C28H33N7O2 and a molecular weight of 499.61 g/mol.
Based on its molecular formula C28H33N7O2, Osimertinib contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 499.61 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Osimertinib under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C28H33N7O2 |
| Molecular Weight | 499.61 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 7 |
Related Osimertinib Standards
- Osimertinib Impurity 20 (CAS 2044702-65-8)
- Osimertinib Impurity 96 (CAS CATO-C4X-204596)
- Osimertinib Impurity 99 (CAS CATO-C4X-204599)
- Osimertinib Impurity 98 (CAS CATO-C4X-204598)
- Osimertinib-13CD3 (CAS 2254100-49-5)
- Osimertinib Impurity 60 (CAS CATO-C4X-204560)
- Osimertinib D6 (CAS 1638281-44-3)
- Osimertinib-4 (CAS 1805787-93-2)
Recommended Standards
- 4-(Acridin-9-ylamino)-N-(2-(acridin-9-ylamino)ethyl)butanamide (CAS 94731-72-3)
- Ibrutinib Impurity 128 (CAS 2190506-56-8)
- N-(3-Carbamoyl-5-phenylthiophen-2-yl)-1-((4-methoxyphenyl)sulfonyl)piperidine-3-carboxamide (CAS 952843-69-5)
- 4-(4-(Benzyloxy)-2-methylbenzoyl)-1-(2-(diethylamino)ethyl)-3-hydroxy-5-(pyridin-4-yl)-1H-pyrrol-2(5H)-one (CAS 488132-09-8)
- 2-Amino-N-cyclopropylethane-1-sulfonamide (CAS 953880-80-3)
- 1-(2-Methoxyethyl)-1h-indole-2-carboxylic acid (CAS 136382-30-4)
- 1-(tert-Butyl)-3-(5-(ethylthio)-1,3,4-thiadiazol-2-yl)urea (CAS 886938-57-4)
- 2-(3-Fluoro-5-(trifluoromethoxy)phenyl)acetonitrile (CAS 1352999-52-0)
- 2-(3-Chlorophenoxy)butanoic acid (CAS 17431-95-7)
- 4-Ethyl-1-methyl-1h,2'h-[3,3'-bipyrazol]-5-amine (CAS 2022842-92-6)
- Tert-butyl 4-(6-fluoropyridin-3-yl)piperidine-1-carboxylate (CAS 741683-17-0)
- 4-Amino-N-(2-hydroxyethyl)-N-(pyrimidin-2-yl)benzenesulfonamide (CAS 169263-66-5)
- Benzyl pyrrolidin-3-ylcarbamatehydrochloride (CAS 553672-38-1)
- Des-Ala21-Tirzepatide (CAS CATO-CPTD788952)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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