2-Nitrothiophene-3-sulfonamide CAS 1421601-53-7
| CAS No. | 1421601-53-7 |
| Molecular Formula | C4H4N2O4S2 |
| Molecular Weight | 208.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Nitrothiophene-3-sulfonamide (CAS 1421601-53-7) is a high-purity analytical reference standard with the molecular formula C4H4N2O4S2 and a molecular weight of 208.22 g/mol.
2-Nitrothiophene-3-sulfonamide (C4H4N2O4S2) contains a carbohydrate-derived structure, an amide group, a sulfone group. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Nitrothiophene-3-sulfonamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C4H4N2O4S2 |
| Molecular Weight | 208.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Nitrothiophene Standards
- 5-Nitrothiophene-2-sulfonamide (CAS 17510-82-6)
- 5-Nitrothiophene-3-sulfonamide (CAS 55673-75-1)
- Ethyl 5-nitrothiophene-3-carboxylate (CAS 100958-70-1)
- EThyl 4-nitrothiophene-2-carboxylate (CAS 66117-32-6)
- Ethyl 5-nitrothiophene-2-carboxylate (CAS 5751-84-8)
- 3-Nitrothiophene-2,5-dicarboxylic acid (CAS 1437794-39-2)
- 2-Nitrothiophene-3,4-dicarboxylic acid (CAS 932032-15-0)
- 5-Methyl-4-nitrothiophene-2-sulfonamide (CAS 905839-54-5)
Recommended Standards
- (S)-2-(1-amino-3-hydroxypropyl)pyrrolo[2,1-f][1,2,4]triazin-4(1H)-one (CAS 1403949-10-9)
- 5-Ethyl-5-(1-methyl-1h-pyrazol-4-yl)imidazolidine-2,4-dione (CAS 1423029-14-4)
- 3-Nicotinoylbenzonitrile (CAS 140182-36-1)
- 5-Amino-3-(3-nitrophenyl)pyrazole (CAS 142338-69-0)
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- 3-[(3-Methoxyphenyl)methyl]-pyrrolidine hydrochloride (CAS 887594-85-6)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com