(αS)-4-Methyl-α-(trifluoromethyl)-2-thiazolemethanol CAS 1421607-35-3
| CAS No. | 1421607-35-3 |
| Molecular Formula | C6H6F3NOS |
| Molecular Weight | 197.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of (αS)-4-Methyl-α-(trifluoromethyl)-2-thiazolemethanol (C6H6F3NOS) is characterized by an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies (αS)-4-Methyl-α-(trifluoromethyl)-2-thiazolemethanol (CAS 1421607-35-3), a certified reference material (molecular formula C6H6F3NOS, MW 197.18 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (αS)-4-Methyl-α-(trifluoromethyl)-2-thiazolemethanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H6F3NOS |
| Molecular Weight | 197.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Recommended Standards
- (1R)-2,2,2-trifluoro-1-(4-methyl-1,3-thiazol-2-yl)ethan-1-ol (CAS 1394051-21-8)
- 4-(2,5-Difluorophenyl)pyrrolidin-2-one (CAS 1470554-60-9)
- 2-[2-(Trifluoromethyl)-1,3-thiazol-5-yl]ethan-1-ol (CAS 1393570-56-3)
- (2-Methyl-4-(trifluoromethyl)thiazol-5-yl)methanol (CAS 14857-19-3)
- Palonosetron-3-ene (CAS 135729-56-5)
- 2-((2-Fluorophenoxy)methyl)thiazole-4-carboxylic acid (CAS 1045283-48-4)
- 4-((((9h-Fluoren-9-yl)methoxy)carbonyl)amino)-3-methoxybenzoic acid (CAS 254737-60-5)
- 4-Bromo-N-methyl-2-(trifluoromethyl)aniline hydrochloride (CAS 1215206-44-2)
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