1-(1,8-Dioxa-4,11-diazaspiro[5.6]dodecan-4-yl)ethan-1-one CAS 1422065-15-3
| CAS No. | 1422065-15-3 |
| Molecular Formula | C10H18N2O3 |
| Molecular Weight | 214.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-(1,8-Dioxa-4,11-diazaspiro[5.6]dodecan-4-yl)ethan-1-one (C10H18N2O3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
1-(1,8-Dioxa-4,11-diazaspiro[5.6]dodecan-4-yl)ethan-1-one (CAS 1422065-15-3) is a high-purity analytical reference standard with the molecular formula C10H18N2O3 and a molecular weight of 214.26 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H18N2O3 |
| Molecular Weight | 214.26 g/mol |
| Appearance | White to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 2 |
Related Dioxa Standards
- 1-(1,8-Dioxa-4,11-diazaspiro[5.6]dodecan-11-yl)ethan-1-one (CAS 1422065-61-9)
- 1,4-Dioxa-spiro[4.5]decane-7-carboxylic acid ethyl ester (CAS 412025-07-1)
- 1,4-dioxa-10-azadispiro[4.2.4⁸.2⁵]tetradecan-9-one (CAS 1292278-70-6)
- 1,4-Dioxa-9-azadispiro[4.1.4.3]tetradecan-10-one (CAS 1638759-75-7)
- 1,4-Dioxa-10-azadispiro[4.2.48.25]tetradecan-11-one (CAS 914780-95-3)
- 1,4-Dioxa-9-azadispiro[4.1.47.35]tetradecan-8-one (CAS 2393918-59-5)
- 1,4-Dioxa-9-azadispiro[4.2.48.25]tetradecan-10-one (CAS 686723-63-7)
- 4,7-dioxa-13-azatricyclo[8.5.0.0^{3,8}]pentadeca-1(10),2,8-trien-12-one (CAS 1209081-98-0)
Recommended Standards
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- Semaglutide impurity 71 (CAS CATO-C4X-222671)
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