2-Benzyl-2H-spiro[benzo[d]isothiazole-3,3'-pyrrolidine] 1,1-dioxide CAS 1422137-41-4

Purity 97%+In StockPharmaceutical Standards
CAS No.1422137-41-4
Molecular FormulaC17H18N2O2S
Molecular Weight314.40 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Benzyl-2H-spiro[benzo[d]isothiazole-3,3'-pyrrolidine] 1,1-dioxide CAS 1422137-41-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 314.40 g/mol gives 2-Benzyl-2H-spiro[benzo[d]isothiazole-3,3'-pyrrolidine] 1,1-dioxide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-Benzyl-2H-spiro[benzo[d]isothiazole-3,3'-pyrrolidine] 1,1-dioxide (CAS 1422137-41-4) is a high-purity analytical reference standard with the molecular formula C17H18N2O2S and a molecular weight of 314.40 g/mol.

The molecular framework of 2-Benzyl-2H-spiro[benzo[d]isothiazole-3,3'-pyrrolidine] 1,1-dioxide (C17H18N2O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Benzyl-2H-spiro[benzo[d]isothiazole-3,3'-pyrrolidine] 1,1-dioxide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC17H18N2O2S
Molecular Weight314.40 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Nitrogen Atoms2
Sulfur Atoms1

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