3-(1-Methyl-4-(pyrimidin-2-yl)piperazin-2-yl)-[1,2,4]triazolo[4,3-a]pyridine-6-carboxylic acid CAS 1422140-00-8
| CAS No. | 1422140-00-8 |
| Molecular Formula | C16H17N7O2 |
| Molecular Weight | 339.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(1-Methyl-4-(pyrimidin-2-yl)piperazin-2-yl)-[1,2,4]triazolo[4,3-a]pyridine-6-carboxylic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-(1-Methyl-4-(pyrimidin-2-yl)piperazin-2-yl)-[1,2,4]triazolo[4,3-a]pyridine-6-carboxylic acid (CAS 1422140-00-8), molecular formula C16H17N7O2 and molecular weight 339.35 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, 3-(1-Methyl-4-(pyrimidin-2-yl)piperazin-2-yl)-[1,2,4]triazolo[4,3-a]pyridine-6-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 339.35 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H17N7O2 |
| Molecular Weight | 339.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 7 |
Related Methyl Standards
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Recommended Standards
- N-(2-(4-Ethyl-6-oxopyrimidin-1(6H)-yl)ethyl)-6-(1H-pyrazol-1-yl)pyridazine-3-carboxamide (CAS 1396861-34-9)
- Boc-Phe(3-CF<SUB>3</SUB>)-OH (CAS 142995-31-1)
- N-{1-[3-(pyrazin-2-yl)-1,2,4-oxadiazol-5-yl]cyclohexyl}furan-2-carboxamide (CAS 1396766-26-9)
- 2-Amino-7,7-dimethyl-4-(4-nitrophenyl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (CAS 144036-35-1)
- 2,2-dioxo-1,3-dihydro-2$l^{6}-benzothiophene-5-sulfonamide (CAS 72007-45-5)
- 1-Phenyl-2-(piperazin-1-yl)ethan-1-one dihydrochloride (CAS 109608-71-1)
- 3-(tert-Butoxy)-4-cyclopropoxybenzonitrile (CAS 1243320-07-1)
- 1-Methyl-1h-pyrazolo[3,4-d]pyrimidine-4-thiol (CAS 6014-06-8)
- 3-(4-Methyl-1-oxophthalazin-2(1H)-yl)propanoic acid (CAS 91393-18-9)
- 2-Bromo-6-chlorothioanisole (CAS 1370025-57-2)
- N-methyl-1-(2-methylimidazo[1,2-a]pyridin-3-yl)methanamine (CAS 857283-58-0)
- Methyl 2-amino-4-(1h-imidazol-1-yl)-2-methylpentanoate (CAS 1342380-37-3)
- b-Amino-3-methylbenzenepropanol (CAS 35373-65-0)
- Cholecystokinin Octapeptide (1-5) (desulfated) (CAS 121880-96-4)
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