2,4-Dichloro-8-fluoroquinoline CAS 1422498-86-9
| CAS No. | 1422498-86-9 |
| Molecular Formula | C9H4Cl2FN |
| Molecular Weight | 216.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,4-Dichloro-8-fluoroquinoline (C9H4Cl2FN) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 2,4-Dichloro-8-fluoroquinoline (CAS 1422498-86-9), a certified reference material (molecular formula C9H4Cl2FN, MW 216.04 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H4Cl2FN |
| Molecular Weight | 216.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Dichloro Standards
- 4,6-Dichloro-8-fluoroquinoline (CAS 1019016-87-5)
- 4,8-Dichloro-6-fluoroquinoline (CAS 1019016-95-5)
- 1,3-Dichloro-6-fluoroisoquinoline (CAS 1041423-26-0)
- 4,6-Dichloro-7-fluoroquinoline (CAS 1065093-04-0)
- 4,8-Dichloro-5-fluoroquinoline (CAS 1065093-06-2)
- 4,8-Dichloro-7-fluoroquinoline (CAS 1065093-08-4)
- 3,4-Dichloro-7-fluoroquinoline (CAS 1204810-51-4)
- 3,4-Dichloro-8-fluoroquinoline (CAS 1204811-28-8)
Recommended Standards
- 6-Bromo-N'-hydroxypyridine-3-carboximidamide (CAS 1415144-06-7)
- N-(6-Bromopyridin-2-yl)formic hydrazide (CAS 1437312-09-8)
- 5-Bromo-N-methylpyrimidine-2-carboxamide (CAS 1346819-04-2)
- 2,3-Dichloro-6-fluoroquinoline (CAS 1447949-04-3)
- 1-(2-Phenoxyethyl)cyclohexan-1-amine (CAS 1082495-94-0)
- 2-Methoxy-1,3-thiazole-5-carboxylic acid (CAS 716362-09-3)
- 2-(2-Fluoro-6-nitrophenyl)propane-1,3-diol (CAS 1131605-32-7)
- n'-(2-Chloroacetyl)-5-ethyl-4-methylthiophene-2-carbohydrazide (CAS 1334146-63-2)
- 1-[4-(2,5-Dimethyl-1h-pyrrol-1-yl)phenyl]ethanone (CAS 83935-45-9)
- 4,4,5,5-Tetramethyl-2-[5-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)furan-2-yl]-1,3,2-dioxaborolane (CAS 2377607-50-4)
- Edoxaban Impurity 102 (CAS 19798-80-2)
- 2-Amino-4-N,N-dimethylaminoaniline, >97% (CAS 85545-58-0)
- 3,4,5-Trimethacarb (CAS 2686-99-9)
- Glucagon (19-29) (human, rat, porcine) (CAS 64790-15-4)
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