2-Difluoromethanesulfonamido-4-methoxybenzene-1-sulfonyl chloride CAS 1423024-75-2
| CAS No. | 1423024-75-2 |
| Molecular Formula | C8H8ClF2NO5S2 |
| Molecular Weight | 335.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-Difluoromethanesulfonamido-4-methoxybenzene-1-sulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-Difluoromethanesulfonamido-4-methoxybenzene-1-sulfonyl chloride (CAS 1423024-75-2), molecular formula C8H8ClF2NO5S2 and molecular weight 335.73 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 2-Difluoromethanesulfonamido-4-methoxybenzene-1-sulfonyl chloride is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 335.73 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H8ClF2NO5S2 |
| Molecular Weight | 335.73 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Difluoromethanesulfonamido Standards
Recommended Standards
- 2-amino-N-[2-chloro-5-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazole-5-carboxamide (CAS 1411227-49-0)
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- Nonadecanoic-d37 Acid (CAS 1219798-49-8)
- 2-[(Benzenesulfonyl)methyl]-3-chloro-5-(trifluoromethyl)pyridine (CAS 338420-49-8)
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- Firocoxib Impurity 1 (CAS 204390-60-3)
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- 3-(Azetidin-3-yloxy)-N,N-dimethylpropanamide (CAS 1343328-41-5)
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- 2-((1-Methyl-1h-tetrazol-5-yl)thio)-N-(3-(trifluoromethyl)phenyl)acetamide (CAS 271798-73-3)
- Des-Asp15-Tirzepatide (CAS CATO-CPTD788958)
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