3-Chloro-n-(piperidin-3-ylmethyl)pyridine-4-carboxamide dihydrochloride CAS 1423025-22-2

Purity 97%+In StockPharmaceutical Standards
CAS No.1423025-22-2
Molecular FormulaC12H16ClN3O
Molecular WeightN/A
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-Chloro-n-(piperidin-3-ylmethyl)pyridine-4-carboxamide dihydrochloride CAS 1423025-22-2 chemical structure

Description

The occurrence of 3-Chloro-n-(piperidin-3-ylmethyl)pyridine-4-carboxamide dihydrochloride is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

3-Chloro-n-(piperidin-3-ylmethyl)pyridine-4-carboxamide dihydrochloride (CAS 1423025-22-2) is a high-purity analytical reference standard with the molecular formula C12H16ClN3OHCl and a molecular weight of 290.19 g/mol.

The molecular framework of 3-Chloro-n-(piperidin-3-ylmethyl)pyridine-4-carboxamide dihydrochloride (C12H16ClN3OHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC12H16ClN3O 2*HCl
Molecular Weight290.19 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentCl-containing
Nitrogen Atoms3

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