4-(chlorosulfonyl)-2-(trifluoromethyl)benzoic acid CAS 1423031-79-1
| CAS No. | 1423031-79-1 |
| Molecular Formula | C8H4ClF3O4S |
| Molecular Weight | 288.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-(chlorosulfonyl)-2-(trifluoromethyl)benzoic acid (CAS 1423031-79-1), molecular formula C8H4ClF3O4S and molecular weight 288.63 g/mol, is a CATO reference standard with documented purity and traceability.
4-(chlorosulfonyl)-2-(trifluoromethyl)benzoic acid (C8H4ClF3O4S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H4ClF3O4S |
| Molecular Weight | 288.63 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
Related chlorosulfonyl Standards
- Methyl 5-(chlorosulfonyl)-2,3,4-trifluorobenzoate (CAS 2137649-82-0)
- Methyl 1-(4-(chlorosulfonyl)phenyl)cyclobutane-1-carboxylate (CAS 2407349-26-0)
- Methyl 3-(chlorosulfonyl)-1-methyl-1h-indole-2-carboxylate (CAS 1423030-96-9)
- 6-(Chlorosulfonyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 876303-38-7)
- Methyl (5-chlorosulfonyl-1H-benzimidazol-2-yl)carbamate (CAS 79213-74-4)
- ethyl 4-[(chlorosulfonyl)methyl]-4-fluorocyclohexane-1-carboxylate (CAS 1955498-99-3)
- 6-(Chlorosulfonyl)-2-hydroxy-1-naphthoic acid (CAS 70714-67-9)
- ethyl 6-(chlorosulfonyl)-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxylate (CAS 1803591-20-9)
Recommended Standards
- 5-(Trifluoroacetamido)pyridine-2-sulfonyl chloride (CAS 1215906-69-6)
- 2-Chloro-4-Formylphenyl Trifluoromethanesulfonate (CAS 188112-72-3)
- 7-Chloro-1,1,1-Trifluoro-2-(Trifluoromethyl)Heptane-2,4-Diol (CAS 101913-68-2)
- 3-Chloro-5-((trifluoromethyl)sulfonyl)benzoic acid (CAS 2378554-12-0)
- 2-Ethyl-2-methylbenzo[d][1,3]dioxol-5-ol (CAS 74024-81-0)
- 1-Allyl-1H-benzo[d][1,2,3]triazole (CAS 52298-91-6)
- 1H,4H,5H,6H,7H,8H-Pyrrolo[3,2-c]azepine (CAS 50615-14-0)
- (S)-1-Cyclopentyl-3-methyl-piperazine (CAS 1187929-76-5)
- (R)-1-(5,8-Dihydroxy-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-4-methylpent-3-en-1-yl propionate (CAS 162283-70-7)
- 3-Bromo-5-(2-chloroethyl)pyridine (CAS 1260678-97-4)
- 4-Iodo-2-methoxyphenol (CAS 203861-62-5)
- methyl (2R,4S)-4-azidopyrrolidine-2-carboxylate (CAS 1464217-42-2)
- tert-Butyl 2-Hydroxypropanoate (CAS 59854-10-3)
- Insulin Degludec Impurity 18 (CAS CATO-C4X-215718)
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