Methyl 3-amino-6-fluorobenzo[b]thiophene-2-carboxylate CAS 142363-99-3

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl 3-amino-6-fluorobenzo[b]thiophene-2-carboxylate.

Methyl 3-amino-6-fluorobenzo[b]thiophene-2-carboxylate (CAS 142363-99-3), molecular formula C10H8FNO2S and molecular weight 225.24 g/mol, is a CATO reference standard with documented purity and traceability.

Methyl 3-amino-6-fluorobenzo[b]thiophene-2-carboxylate (C10H8FNO2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures Methyl 3-amino-6-fluorobenzo[b]thiophene-2-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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