| CAS No. | 1424533-72-1 |
| Molecular Formula | C9H10ClN3S |
| Molecular Weight | 227.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Compared with other compounds in its class, the molecular weight of 227.71 g/mol gives 3-Chloro-5-(cyclopentylamino)-1,2-thiazole-4-carbonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-Chloro-5-(cyclopentylamino)-1,2-thiazole-4-carbonitrile (CAS 1424533-72-1) is a high-purity analytical reference standard with the molecular formula C9H10ClN3S and a molecular weight of 227.71 g/mol.
The molecular framework of 3-Chloro-5-(cyclopentylamino)-1,2-thiazole-4-carbonitrile (C9H10ClN3S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Chloro-5-(cyclopentylamino)-1,2-thiazole-4-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
| Molecular Formula | C9H10ClN3S |
| Molecular Weight | 227.71 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |