1-(2-Fluorobenzyl)piperidine CAS 1426-74-0
| CAS No. | 1426-74-0 |
| Molecular Formula | C12H16FN |
| Molecular Weight | 193.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(2-Fluorobenzyl)piperidine.
1-(2-Fluorobenzyl)piperidine (CAS 1426-74-0) is a high-purity analytical reference standard with the molecular formula C12H16FN and a molecular weight of 193.26 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, 1-(2-Fluorobenzyl)piperidine is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 193.26 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H16FN |
| Molecular Weight | 193.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluorobenzyl Standards
- N-(4-fluorobenzyl)-N-methylcyclobutanamine (CAS 1096278-20-4)
- 1-(4-Fluorobenzyl)piperidine (CAS 139592-92-0)
- (1-(4-Fluorobenzyl)cyclobutyl)methanamine (CAS 1439896-37-3)
- 2-(2-Fluorobenzyl)-2-methylpyrrolidine (CAS 1512648-78-0)
- 4-(2-fluorobenzyl)piperidine (CAS 194288-97-6)
- (R)-3-(4-Fluorobenzyl)piperidine (CAS 794464-41-8)
- (S)-3-(4-Fluorobenzyl)piperidine (CAS 275815-80-0)
- 1-(3-Fluorobenzyl)piperidine (CAS 891400-75-2)
Recommended Standards
- N,3-dimethyltetrahydro-2h-pyran-4-sulfonamide (CAS 1421000-23-8)
- n-Ethyl-6-fluoro-1,2,3,4-tetrahydronaphthalen-1-amine (CAS 1427378-68-4)
- 2-(oxan-4-yl)ethane-1-sulfonamide (CAS 1420955-11-8)
- {1-[(2-Fluorophenyl)methyl]cyclobutyl}methanamine (CAS 1439896-92-0)
- (5-Bromo-2-(trifluoromethoxy)phenyl)(pyridin-4-yl)methanone (CAS 1261805-90-6)
- 5-benzylpiperidin-2-one (CAS 906624-61-1)
- 1-(2,2,2-Trifluoroethyl)piperidin-4-amine dihydrochloride (CAS 1177271-15-6)
- N-(2-Aminoethyl)carbamodithioic Acid (CAS 20950-84-9)
- 2-Chloro-n-cyclohexyl-n-methylpyrimidin-4-amine (CAS 1248370-43-5)
- N-(Pyrimidin-4-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide (CAS 1419221-36-5)
- methyl 2-cyano-2-methyl-2-phenylacetate (CAS 79341-72-3)
- 2-((1-(Pyridin-4-yl)ethyl)amino)ethan-1-ol (CAS 1038369-00-4)
- Dapagliflozin Impurity 223 (CAS CATO-C4X-1138223)
- Osteoblast-Adhesive Peptide (CAS 193613-75-1)
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