5-Fluoro-3-iodo-6-methyl-1H-pyrazolo[3,4-b]pyridine CAS 1426309-26-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1426309-26-3
Molecular FormulaC7H5FIN3
Molecular Weight277.04 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Fluoro-3-iodo-6-methyl-1H-pyrazolo[3,4-b]pyridine CAS 1426309-26-3 chemical structure

Description

The occurrence of 5-Fluoro-3-iodo-6-methyl-1H-pyrazolo[3,4-b]pyridine is closely related to a nitrile group, fluorine/iodine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 5-Fluoro-3-iodo-6-methyl-1H-pyrazolo[3,4-b]pyridine (CAS 1426309-26-3), a certified reference material (molecular formula C7H5FIN3, MW 277.04 g/mol) for analytical method development and quality control.

The molecular framework of 5-Fluoro-3-iodo-6-methyl-1H-pyrazolo[3,4-b]pyridine (C7H5FIN3) is characterized by a nitrile group, fluorine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC7H5FIN3
Molecular Weight277.04 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentF/I-containing
Nitrogen Atoms3

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