(2,2-Difluorocyclopropyl)methanamine hydrochloride CAS 1426309-49-0
| CAS No. | 1426309-49-0 |
| Molecular Formula | C4H7F2N |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(2,2-Difluorocyclopropyl)methanamine hydrochloride (CAS 1426309-49-0), molecular formula C4H7F2NHCl and molecular weight 143.56 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (2,2-Difluorocyclopropyl)methanamine hydrochloride (C4H7F2NHCl) is characterized by fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4H7F2N HCl |
| Molecular Weight | 143.56 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Difluorocyclopropyl Standards
- 2-(2,2-difluorocyclopropyl)ethanol (CAS 117284-59-0)
- 5-(2,2-Difluorocyclopropyl)-1h-pyrazol-3-amine (CAS 1186609-07-3)
- 2-(2,2-difluorocyclopropyl)acetic acid (CAS 123131-67-9)
- 2-(2,2-Difluorocyclopropyl)ethan-1-amine (CAS 123131-70-4)
- 1-((2,2-Difluorocyclopropyl)methoxy)-4-nitrobenzene (CAS 1236764-09-2)
- (2,2-Difluorocyclopropyl)methanesulfonyl chloride (CAS 1260671-57-5)
- (2,2-Difluorocyclopropyl)benzene (CAS 13343-40-3)
- 4-((2,2-Difluorocyclopropyl)methyl)piperazin-2-one (CAS 1393541-17-7)
Recommended Standards
- 1-(O-tolyl)prop-2-en-1-one (CAS 39627-60-6)
- 3-Bromo-2,4-dimethoxybenzonitrile (CAS 1891994-61-8)
- (R)-2-(4-chloro-2-fluoro-5-nitrophenyl)pyrrolidine (CAS 1389909-70-9)
- Cefuroxime impurity 106 (CAS CATO-C4X-1245106)
- (2-Bromophenyl)(3,4-dichlorophenyl)methanol (CAS 1284404-29-0)
- (5aR,10bS)-2-(2,6-Diethylphenyl)-5a,10b-dihydro-4H,6H-indeno[2,1-b][1,2,4]triazolo[4,3-d][1,4]oxazin-2-iumtetrafluoroborate (CAS 1221487-76-8)
- 5-Nitro-2-(p-tolyl)-1H-benzo[d]imidazole (CAS 1571-90-0)
- Thiophen-2-yl(o-tolyl)methanone (CAS 6933-35-3)
- Tert-butyl 5-benzyl-2,5,8-triazaspiro[3.5]Nonane-2-carboxylate (CAS 1823863-23-5)
- Des-Ile17-Tirzepatide (CAS CATO-CPTD788956)
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