Ethyl 5-amino-1-(2-(trifluoromethoxy)phenyl)-1H-pyrazole-3-carboxylate CAS 1427010-48-7
| CAS No. | 1427010-48-7 |
| Molecular Formula | C13H12F3N3O3 |
| Molecular Weight | 315.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Ethyl 5-amino-1-(2-(trifluoromethoxy)phenyl)-1H-pyrazole-3-carboxylate (C13H12F3N3O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Ethyl 5-amino-1-(2-(trifluoromethoxy)phenyl)-1H-pyrazole-3-carboxylate (CAS 1427010-48-7), a certified reference material (molecular formula C13H12F3N3O3, MW 315.25 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Ethyl 5-amino-1-(2-(trifluoromethoxy)phenyl)-1H-pyrazole-3-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H12F3N3O3 |
| Molecular Weight | 315.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Ethyl Standards
- Ethyl 5-amino-1-(4-(trifluoromethoxy)phenyl)-1H-pyrazole-3-carboxylate (CAS 1369271-77-1)
- Ethyl 5-amino-1-(3-(trifluoromethoxy)phenyl)-1H-pyrazole-3-carboxylate (CAS 1427013-50-0)
- Ethyl 5-amino-1-(4-(trifluoromethoxy)phenyl)-1h-pyrazole-4-carboxylate (CAS 400073-87-2)
- (S)-2-Amino-N-cyclopropyl-N-(3,4-dichlorobenzyl)-3-methylbutanamide (CAS 1308506-38-8)
- (S)-2-Amino-N-cyclopropyl-N-(2,4-dichlorobenzyl)-3-methylbutanamide (CAS 1353995-76-2)
- (S)-2-Amino-N-cyclopropyl-N-(2,6-dichlorobenzyl)-3-methylbutanamide (CAS 1354007-16-1)
- (S)-2-Amino-N-cyclopropyl-N-(2,5-dichlorobenzyl)-3-methylbutanamide (CAS 1354015-21-6)
- (S)-2-Amino-N-cyclopropyl-N-(2,3-dichlorobenzyl)-3-methylbutanamide (CAS 1354020-52-2)
Recommended Standards
- Furan-2-yl(4-(5-(trifluoromethyl)-1,3,4-oxadiazol-2-yl)piperidin-1-yl)methanone (CAS 1396800-72-8)
- methyl 1-{[4-(2,2,2-trifluoroethoxy)phenyl]methyl}-1H-1,2,4-triazole-3-carboxylate (CAS 1376269-34-9)
- 1-(5-(Trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)piperidine-4-carboxylic acid (CAS 1707594-13-5)
- 4-Bromo-5-(octyloxy)benzene-1,2-diamine (CAS 1373232-59-7)
- Ethyl 6-methoxy-2-methyl-4-oxo-1(4H)-quinolineacetate (CAS 384362-33-8)
- 5-(Dimethylamino)pent-3-yn-1-ol (CAS 104602-35-9)
- 1-Ethyl-5-(4-methylphenyl)-1h-imidazole-2-thiol (CAS 852388-94-4)
- 1,3-Benzenedicarboxylic acid, polymer with (9Z,12Z)-9,12-octadecadienoic acid dimer and 1,2-propanediol (CAS 68400-68-0)
- 4-(Piperidin-3-yl)benzamide hydrochloride (CAS 2301169-19-5)
- Imidazo[1,2-a]pyridine-3-ethanol, 3-methanesulfonate (CAS 1189154-20-8)
- 1-(3-Fluorobenzoyl)-1H-indole-3-carbaldehyde (CAS 1267698-09-8)
- Trazodone Impurity 48 HCl (CAS CATO-C4X-177248)
- N-(2,5-Dimethoxyphenyl)-2-(6-(4-fluorophenyl)imidazo[2,1-b]thiazol-3-yl)acetamide (CAS 897464-88-9)
- (Leu31,Pro3?)-Neuropeptide Y (human, rat) trifluoroacetate salt (CAS 132699-73-1)
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