7-fluoro-4-methoxy-2-methyl-1H-indole CAS 1427366-48-0
| CAS No. | 1427366-48-0 |
| Molecular Formula | C10H18FNO |
| Molecular Weight | 187.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
7-fluoro-4-methoxy-2-methyl-1H-indole (CAS 1427366-48-0), molecular formula C10H18FNO and molecular weight 187.25 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 7-fluoro-4-methoxy-2-methyl-1H-indole (C10H18FNO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 7-fluoro-4-methoxy-2-methyl-1H-indole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H18FNO |
| Molecular Weight | 187.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
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