4-Bromo-6-chlorobenzofuran CAS 1427377-74-9
| CAS No. | 1427377-74-9 |
| Molecular Formula | C8H4BrClO |
| Molecular Weight | 231.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-Bromo-6-chlorobenzofuran meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
4-Bromo-6-chlorobenzofuran (CAS 1427377-74-9) is a high-purity analytical reference standard with the molecular formula C8H4BrClO and a molecular weight of 231.47 g/mol.
The molecular framework of 4-Bromo-6-chlorobenzofuran (C8H4BrClO) is characterized by a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H4BrClO |
| Molecular Weight | 231.47 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl/Br-containing |
Related Bromo Standards
- 5-Bromo-7-chlorobenzofuran (CAS 1194375-29-5)
- 7-Bromo-3-chlorobenzofuran (CAS 1368229-56-4)
- 5-Bromo-4-chloro-1-benzofuran (CAS 1427324-99-9)
- 6-Bromo-5-chloro-1-benzofuran (CAS 1427368-44-2)
- 7-Bromo-6-chloro-1-benzofuran (CAS 1427404-45-2)
- 4-Bromo-5-chloro-1-benzofuran (CAS 1427405-29-5)
- 2-Bromo-7-chlorobenzofuran (CAS 2274076-22-9)
- 3-Bromo-5-chlorobenzofuran (CAS 36739-99-8)
Recommended Standards
- 2,4,6-Trichloroisophthalonitrile (CAS 19861-59-7)
- 4,5,6-Trichloroisophthalonitrile (CAS 124739-66-8)
- Bromononylmagnesium (1.0 M in diethyl ether) (CAS 39691-62-8)
- 3-Bromo-6-chlorobenzofuran (CAS 36739-97-6)
- 2-(3,4-Difluorophenyl)-1-isopropylpyrrolidin-3-amine (CAS 1443981-95-0)
- (5Z)-5-[(Furan-2-yl)methylidene]-2-(methylsulfanyl)-4,5-dihydro-1,3-thiazol-4-one (CAS 866050-12-6)
- N-(4-Fluoro-3-methoxyphenyl)-4-hydroxybenzene-1-sulfonamide (CAS 1711256-77-7)
- 3-Amino-2-[(pyridin-4-yl)methyl]propanoic acid (CAS 910444-19-8)
- 1-(1-(Dodecyloxy)-2-methylpropyl)-1H-benzo[d][1,2,3]triazole (CAS 314273-15-9)
- 1-[(4-Nitrophenyl)methyl]-1,4-diazepane (CAS 118158-53-5)
- Glucametacin, 98% (CAS 871014-84-5)
- 1-(3-Methoxybenzyl)-4-methyl-1H-pyrazol-5-amine (CAS 1152526-41-4)
- 3,5-Dimethyl-1-(2-(methylsulfonyl)ethyl)-1h-pyrazol-4-amine (CAS 1183447-41-7)
- Insulin Degludec Impurity 1 (CAS 843666-26-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com