2-[4-(trifluoromethyl)piperidin-1-yl]acetic acid hydrochloride CAS 1427378-67-3

Description

Compared with other compounds in its class, the molecular weight of 247.64 g/mol gives 2-[4-(trifluoromethyl)piperidin-1-yl]acetic acid hydrochloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-[4-(trifluoromethyl)piperidin-1-yl]acetic acid hydrochloride (CAS 1427378-67-3), molecular formula C8H12F3NO2HCl and molecular weight 247.64 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-[4-(trifluoromethyl)piperidin-1-yl]acetic acid hydrochloride (C8H12F3NO2HCl) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-[4-(trifluoromethyl)piperidin-1-yl]acetic acid hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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