5-Amino-1-methyl-6-(thiophen-2-yl)piperidin-2-one hydrochloride CAS 1427378-76-4
| CAS No. | 1427378-76-4 |
| Molecular Formula | C10H14N2OS |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
5-Amino-1-methyl-6-(thiophen-2-yl)piperidin-2-one hydrochloride (CAS 1427378-76-4) is a high-purity analytical reference standard with the molecular formula C10H14N2OSHCl and a molecular weight of 246.75 g/mol.
The molecular framework of 5-Amino-1-methyl-6-(thiophen-2-yl)piperidin-2-one hydrochloride (C10H14N2OSHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 5-Amino-1-methyl-6-(thiophen-2-yl)piperidin-2-one hydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H14N2OS HCl |
| Molecular Weight | 246.75 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Amino Standards
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Recommended Standards
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- Lifitegrast Impurity 173 (CAS CATO-C4X-2409173)
- (S)-12-((R)-10-Chloro-6,11-dihydrodibenzo[b,e]thiepin-11-yl)-7-hydroxy-3,4,12,12a-tetrahydro-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazine-6,8-dione (CAS 1370244-54-4)
- 1-[(2R)-2-aminopropyl]-3-methyl-azetidin-3-ol;dihydrochloride (CAS 2703748-98-3)
- Methyl 4-Fluoroindole-3-carboxylate (CAS 1220039-52-0)
- a2,3-Sialylglycopeptide (CAS 189035-43-6)
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