2-Methyl-6-(trifluoromethyl)pyridine-3-sulfonamide CAS 1427461-10-6

Purity 97%+In StockPharmaceutical Standards
CAS No.1427461-10-6
Molecular FormulaC7H7F3N2O2S
Molecular Weight240.20 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Methyl-6-(trifluoromethyl)pyridine-3-sulfonamide CAS 1427461-10-6 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 240.20 g/mol gives 2-Methyl-6-(trifluoromethyl)pyridine-3-sulfonamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-Methyl-6-(trifluoromethyl)pyridine-3-sulfonamide (CAS 1427461-10-6), molecular formula C7H7F3N2O2S and molecular weight 240.20 g/mol, is a CATO reference standard with documented purity and traceability.

2-Methyl-6-(trifluoromethyl)pyridine-3-sulfonamide (C7H7F3N2O2S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC7H7F3N2O2S
Molecular Weight240.20 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentF-containing
Nitrogen Atoms2
Sulfur Atoms1

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